Aspergillus nidulans VeA subcellular localization is dependent on the importin ? carrier and on light

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Secondary Metabolism and Development Is Mediated by LlmF Control of VeA Subcellular Localization in Aspergillus nidulans

Secondary metabolism and development are linked in Aspergillus through the conserved regulatory velvet complex composed of VeA, VelB, and LaeA. The founding member of the velvet complex, VeA, shuttles between the cytoplasm and nucleus in response to alterations in light. Here we describe a new interaction partner of VeA identified through a reverse genetics screen looking for LaeA-like methyltr...

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The Aspergillus nidulans rcoA gene is required for veA-dependent sexual development.

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The expression of sterigmatocystin and penicillin genes in Aspergillus nidulans is controlled by veA, a gene required for sexual development.

Secondary metabolism is commonly associated with morphological development in microorganisms, including fungi. We found that veA, a gene previously shown to control the Aspergillus nidulans sexual/asexual developmental ratio in response to light, also controls secondary metabolism. Specifically, veA regulates the expression of genes implicated in the synthesis of the mycotoxin sterigmatocystin ...

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ژورنال

عنوان ژورنال: Molecular Microbiology

سال: 2007

ISSN: 0950-382X,1365-2958

DOI: 10.1111/j.1365-2958.2006.05506.x